Doctors surprised by probe linking Singulair to suicide
The federal Food and Drug Administration is studying
a possible link between Singulair, Merck &Co.'s hugely popular asthma
drug, and suicide.The agency will review reports it received about behavior
and mood changes, suicidal thoughts and suicide itself among patients on
the drug.The FDA did not say how many reports it had received. Merck noted
it was a "very limited number"involving both adults and children.
FDA looks into Singulair, risks of suicidal thoughts,
Anecdotal reports from doctors, patients studied
The Food and Drug Administration is investigating
anecdotal reports that people who use Singulair, the popular asthma and
allergy drug, are at greater risk for suicidal thoughts and suicide. Singulair
is a pill prescribed to treat asthma and hay fever symptoms such as sneezing
and a nose that is stuffy, runny or itchy. It blocks an inflammation pathway
in the body that can cause both asthma and allergy symptoms.It was approved
for treating asthma in 1998 .
Merck sued over patent on allergy drug Singulair
The battle over the patent on Merck and Co.'s
allergy and asthma drug Singulair, the best-selling drug of one of the
world's largest drug makers, continued Friday as a group of drug distributors
and health insurers sued Merck. The filers say Merck should never have
been awarded one of the key patents supporting the drug, and that is has
wrongfully intimidated rivals by suing them for patent infringement, which
has kept competing versions of Singulair from being developed.
Suicides prompt review of allergy drug FDA starts an investigation
into Merck's Singulair
WASHINGTON - The Food and Drug Administration
is investigating a possible link between Merck's best-selling Singulair
and suicide. FDA said Thursday it is reviewing a handful of reports involving
mood changes, suicidal behavior and suicide in patients who have taken
the popular allergy and asthma drug. Merck has updated the drug's labeling
four times in the past year to include information on a range of reported
side effects.
FDA investigates Singulair-suicide link The inquiry is
based on reports, not studies; none of 11,000 patients in 40 drug trials
has committed suicide. The Food and Drug Administration said
Thursday that it is investigating a possible link between Merck's best-selling
Singulair and suicide.FDA said it is reviewing a handful of reports involving
mood changes, suicidal behavior and suicide in patients who have taken
the popular allergy and asthma drug.With sales of $4.3 billion last year,
Singulair is used by millions of patients in the U.S, according to Merck.
Patients With Asthma and Seasonal Allergies Respond Better
to Advair(R) for Their Asthma Than Singulair(TM), Study Suggests
that Adding Singulair to Advair Offers no Additional Improvement in Overall
Asthma Control
PRNewswire-FirstCall -- Patients with both asthma
and allergic rhinitis, or seasonal allergies, experience significantly
better lung function when treated with Advair Diskus(R) (fluticasone propionate
and salmeterol inhalation powder) as compared with Singulair (montelukast
sodium). The results of the 660-subject study were presented today at the
International Conference of the American Thoracic Society meeting in Toronto.
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